Your Online Source for Plant-Based Research Articles

Welcome to plantbasedresearch.org, an online narrative review of peer-reviewed, scientific research papers and educational resources that are relevant to plant-based nutrition. Links to the abstract are included with every article, and links to the free full articles are included when possible! A narrative review is a collection of research papers supporting a particular theory - this website is by no means an exhaustive directory of all research on nutrition and disease but presents the growing body of evidence supporting the theory that whole food, plant-based diets offer the best chance for avoiding chronic disease, and in some cases, reversing it.

To browse scientific papers a variety of topics visit our "Research Articles by Category" page. Please Join Our Newsletter for updates on new studies! Or, do a site search to find information by keyword. Visit the Participate in Research Studies to join the recruitment list for future studies. Thank you for your interest in plant-based nutrition.

 

Methylmalonic Acid Levels and their Relation with Cobalamin Supplementation in Spanish Vegetarians.

Cobalamin deficiency represents a health issue for vegetarians, especially vegans, if supplements are not consumed. Vitamin B12 serum levels, traditionally used to assess the vitamin B12 status, can be normal under functional deficiency conditions. In this regard, methylmalonic acid (MMA) has proven to be a more specific marker to detect subclinical vitamin B12 deficiency. In this study, we present for the first time the cobalamin status of Spanish vegetarians using both vitamin B12 and MMA markers, and the effects of the plant-based diet and the intake of vitamin B12 supplements.

Dietary methionine restriction regulated energy and protein homeostasis by improving thyroid function in high fat diet mice.

Methionine-restricted diets (MRD) show an integrated series of beneficial health effects, including improving insulin sensitivity, limiting fat deposition, and decreasing oxidative stress, and inflammation responses. We aimed to explore the systemic responses to a MRD in mice fed with a high fat (HFD) and clarify the possible mechanism. Mice were fed with a control diet (0.86% methionine + 4% fat, CON), HFD (0.86% methionine + 20% fat), or MRD (0.17% methionine + 20% fat) for 22 consecutive weeks. HFD-fed mice showed widespread systemic metabolic disorders and thyroid dysfunction.

Carbon footprint and nutritional quality of different human dietary choices.

Apart from industrial activities, our eating habits also have a significant environmental cost associated with crop cultivation, manufacturing processes, packaging, refrigeration, transport cooking and waste management. In a context of growing social awareness of the role of different dietary choices in the environment, the review of different alternatives on the road to a healthy and sustainable diet should integrate relevant information on the nutritional quality of different eating habits.

Risk factors for inflammatory bowel disease: A prospective multi-center study.

INTRODUCTION: Environmental risk factors have been associated with inflammatory bowel disease (IBD). With rising incidence, it is important to know risk factors associated with IBD in our population. This study was aimed to evaluate risk factors for IBD from western India. METHODS: This was prospective, multi-center case-control study which included 1054 patients with IBD of which 765 (72.5%) were ulcerative colitis (UC) and 289 (27.4%) Crohn's disease (CD). Asymptomatic individuals without a history of any major illness served as controls.

Dietary non-fermentable fiber prevents autoimmune neurological disease by changing gut metabolic and immune status.

The autoimmune neurological disease, Multiple Sclerosis (MS), have increased at alarming rates in the Western society over the last few decades. While there are numerous efforts to develop novel treatment approaches, there is an unmet need to identify preventive strategies. We explored whether central nervous system (CNS) autoimmunity can be prevented through dietary manipulation using a spontaneous autoimmune encephalomyelitis mouse model.

Flaxseed

Flax (Linum usitatissimum) seed provides a nonabsorbable fiber which has been used as a laxative and has also been used topically to treat various skin conditions. Flaxseed oil contains alpha-linolenic acid (ALA), which is partially converted into the omega-3-fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) in the body. Flaxseed oil increases the ALA content of breastmilk, but does not increase the DHA content.

A Vegetarian Diet Is a Major Determinant of Gut Microbiota Composition in Early Pregnancy.

The composition of the gut microbiota can be influenced by dietary composition. In pregnancy, the maternal gut microbiome has associations with maternal and infant metabolic status. There is little known regarding the impact of a vegetarian diet in pregnancy on maternal gut microbiota. This study explored the gut microbiota profile in women who were vegetarian or omnivorous in early gestation. Women were selected from participants in the Study of PRobiotics IN Gestational diabetes (SPRING) randomised controlled trial.

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