Heart Disease and Stroke

A 48-Hour Vegan Diet Challenge in Healthy Women and Men Induces a BRANCH-Chain Amino Acid Related, Health Associated, Metabolic Signature.

SCOPE:Research is limited on diet challenges to improve health. A short-term, vegan protein diet regimen nutritionally balanced in macronutrient composition compared to an omnivorous diet was hypothesized to improve metabolic measurements of blood sugar regulation, blood lipids, and amino acid metabolism. METHODS AND RESULTS: This randomized, cross-over, controlled vegan verses animal diet challenge was conducted on 21 (11 female,10 male) healthy participants. Fasting plasma was measured during a 3-day diet intervention for clinical biochemistry and metabonomics.

Association of vegetarian diet with inflammatory biomarkers: a systematic review and meta-analysis of observational studies.

OBJECTIVE: Vegetarian diets contain various anti-inflammatory components. We aimed to investigate the effects of vegetarianism on inflammatory biomarkers when compared with omnivores. DESIGN: Systematic review and meta-analysis. SETTING: Literature search was conducted in Science Direct, Proquest, MEDLINE and Google Scholar up to June 2016. Summary estimates and corresponding 95 % CI were derived via the DerSimonian and Laird method using random effects, subgroup analyses were run to find the source of heterogeneity and a fixed-effect model examined between-subgroup heterogeneity.

Ovo-vegetarian diet is associated with lower systemic blood pressure in Taiwanese women.

OBJECTIVE: This study was designed to investigate blood pressure (BP) profiles among Taiwanese women with different dietary patterns. STUDY DESIGN: Cross-sectional study. METHODS: A total of 269 non-hypertensive Taiwanese women, 40 years of age or older, were surveyed using structured questionnaires, and measurements of BP and physiological parameters were made.

Mechanisms involved in cardiovascular protection associated with a vegetarian diet.

Dear Editor: Navarro et al. have carried out a very interesting study to show that a vegetarian diet is associated to lower circulating levels of matrix metalloproteinase (MMP)-2 and MMP-9 in healthy subjects [1]. The findings reported in this study potentially are of major clinical relevance because they strongly suggest that a vegetarian diet may prevent the activation of critical mechanisms involved not only in cardiovascular diseases but also in a variety of malignant neoplastic diseases associated with increased MMP activity [2]. However, we would like to offer...

Plant-Based Nutrition: An Essential Component of Cardiovascular Disease Prevention and Management.

PURPOSE OF REVIEW: This review aims to summarize and discuss the role of plant-based nutrition as an adjunct to the management of cardiovascular disease (CVD). Discussion of nutrition and the benefits of a plant-based diet should be highlighted during healthcare provider visits as an essential part of the overall CVD prevention and management care plan. RECENT FINDINGS: Evidence from prospective cohort studies indicates that a high consumption of predominantly plant-based foods, such as fruit and vegetables, nuts, and whole grains, is associated with a significantly lower risk of CVD.

Effect of a single high-fat meal on endothelial function in healthy subjects.

Although there is a well-established relation between serum cholesterol and coronary artery disease risk, individual and national variations in this association suggest that other factors are involved in atherogenesis. High-fat diet associated triglyceride-rich lipoproteins have also been suggested to be atherogenic.


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