More than coronary artery disease.


Esselstyn CB Jr, Favaloro RG.

Year Published: 



Am J Cardiol.


Study Design: 

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[There is] an unreasonable gap between the medical enthusiasm devoted to acute interventions and the meager efforts currently devoted to secondary prevention. -- Rene C. Favaloro, MD Pioneer of Coronary Artery Bypass Grafting Interventional cardiology is symptomatic treatment. The late Dr. Lewis Thomas referred to this ap proach as "half-way technology," meaning that basic mechanisms of disease were not identified or treated. The bypass operation has significant mortality and morbidity, including further heart damage, stroke, and brain dysfunction. The benefits are at best temporary, since most grafts eventually close, and the patient faces further intervention or a life of progressive dis ability and death from the disease. Angioplasty has a 40% failure rate after 6 months,' as well as significant mortality and morbidity and, frequently, further heart damage.2 Variations to prevent restenosis include stenting with a wire cage, radiation to the balloon- fractured artery to compromise the inflammatory re sponse, or use of a $1,400-per-dose drug to decrease the likelihood of thrombosis ...